Orotic Acid CAS 65-86-1 Anti-Liver Disease and Premature Aging

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Orotic acid CAS 65-86-1 Anti-liver disease and premature aging


Orotic acid is a nutritional drug, also known as vitamin B13. In the 1960s, for the treatment of jaundice and general liver dysfunction. Although in recent years by new drugs instead, but it has to improve liver function, promote liver cell repair and other new features. Such as: to treat gout, improve cerebral blood circulation, increase the activity of phagocytic cells, improve tissue regeneration, help to cure wounds. Can also be used for immunological adjuvant. Can treat chronic X-ray poisoning, as a chemical poisoning prevention and treatment agent.
Other areas, such as the addition of feed, can speed up chick growth and increase egg production. For cosmetics, can reduce skin wrinkles. Add children's food, is conducive to child development. Its derivatives, can make the seeds at low temperatures can also germinate.

Supplement: Product Name: Vitamin B13
Alias: orotic acid, spicy-4-carboxylic acid, 1,2,3,6-tetrahydro-2,6-dioxo-4-pyrimidine carboxylic acid, uracil-6-carboxylic acid, uracil
English name: Orotic acid anhydrous
Chemical Name: 1,2,3,6-tetrahydro-2,6-dioxopyrimidine-4-carboxylic acid;
2,6-Dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid ~ Uracil-4-carboxylic acid.
EINECS: 200-619-8


OOH containing one molecule of crystal water (C5H4N2O4 · H2O, [50887-69-9]) is white needle-like crystals. Mp 345-346 ° C (decomp.). In 100ml of water dissolved through 0.18g, 100ml boiling water can dissolve 13g, very slightly soluble in alcohol and organic solvents, insoluble in ether. Odorless, Pickle.


Orotic acid is a nutritional drug, also known as vitamin B13. It is used as a new type of vitamins in Japan. It is mainly used as a non-prescription drug ingredient and a refreshing drink additive for dry complex vitamins in Japan. In Western Europe, it is not only the composition of medicinal vitamins, but also widely used in cosmetics. It can be used as a nutritive cosmetic matrix. Skin cells, good absorption, promote human cell metabolism, can significantly inhibit skin aging, in the United States on the study of orotic acid more, the use of relatively more in medicine, food, cosmetic, life science fields are applied. China's research and development of orotic acid and application just in the initial stage, the current orotic acid has become the domestic pharmaceutical and biological hot research products, its main purpose is in the medical field.

In the field of medicine, the use of orotic acid and its derivatives widely, in itself is a good liver drug, for jaundice liver disease, fatty liver, acute and chronic hepatitis have a good effect. At home and abroad have been developed to orotic acid-based series of drugs, such as nitro-orotic acid, amino orotic acid, the most promising and market-oriented drug is orotic acid and 5-amino-imidazole-4 - Amide in the salt at 90 ° C, amino acid amine orotate (Akuming), can treat a variety of liver disease, its pharmacological effects and protein synthesis and hematopoietic function, has become the main drug treatment of liver diseases abroad , And the other with purine and promote the development of children with a good promotion effect; In addition, some derivatives of orotic acid on the heart and also has a significant effect. Orotic acid drugs for its good efficacy, side effects, no stimulation of the kidneys, in vivo retention and accumulation of low and other characteristics of popular favor and concern. In recent years, research and development of orotic acid for the synthesis of nucleic acid, nucleic acid is the main material of life for the study of protein biosynthesis and human genetics have a very important significance, has developed a raw material for the production of nucleic acids Health food and drugs, can affect and control many life metabolic activities, to delay human aging has obvious effect.

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